Sharp tip is only needed to penetrate skin epidermis (outer layer). A hypodermic needle with sharp tip opposes the risk of rupturing vessels, or damaging nerves under skin and causing bruising, and swelling.A blunt-tip micro-cannula is a preferred alternative as it pushes away the tissue in front of the tip eliminating the risk of damaging the tissues under skin. Micro-cannulas are therefore, possibly less painful, less invasive and safer compared to hypodermic needles. Micro-cannulas from 18 to 30G are available for injection. Not all centers use micro-cannulas as usually needles are packaged and provided together with the injectable by manufacturers.